TY - T1的结节病的流行病学和卫生成果全民医保人口:一个队列研究摩根富林明-欧洲呼吸杂志》乔和J - 10.1183/13993003.00444 -2019欧元六世- 54 - 4 SP - 1900444 AU -费德勒,Lee m . AU - Balter Meyer AU -费舍尔,茱莲妮h . AU -特蕾莎非盟- Stanbrook,马修·b·AU -革顺,安德里亚Y1 - 2019/10/01 UR - //www.qdcxjkg.com/content/54/4/1900444.abstract N2 - Sarcoidosis-related死亡率上升似乎在北美,女性和老年人增加利率。我们旨在估计趋势结节病发病率、患病率和死亡率在安大略省,加拿大。我们进行了队列研究使用卫生行政来自安大略省1996年和2015年之间的数据。国际疾病分类和安大略健康保险计划代码被用于检出率。创建三个疾病定义:1)结节病,两个或两个以上的医生声称在2年;2)慢性结节病,5个或5个以上医生声称在3年;3)结节病和组织学,两个或两个以上的医生索赔之间的组织切片进行索赔。总的来说,18 550年、9199年和3819人与结节病、慢性结节病和结节病与组织学、分别确定。结节病的患病率是143每100 000年的2015人,增加116%(术中;0.0001)从1996年。增加的年龄调整患病率男性高于女性(136%比99%;术中,0.0001)。 The incidence of sarcoidosis declined from 7.9 to 6.8 per 100 000 between 1996 and 2014 (15% decrease; p=0.0009). A 30.3% decrease in incidence was seen among females (p<0.0001) compared with a 5.5% increase in males (p=0.47). Age- and sex-adjusted mortality rates of patients with sarcoidosis rose from 1.15% to 1.47% between 1996 and 2015 (28% increase; p=0.02), with the overall trend being nonsignificant (p=0.39). Mortality rates in patients with chronic sarcoidosis increased significantly over the study period (p=0.0008).The prevalence of sarcoidosis is rising in Ontario, with an apparent shifting trend in disease burden from females to males. Mortality is increasing in patients with chronic sarcoidosis.The prevalence of sarcoidosis in Canada is increasing, with an estimated rate of 143 per 100 000 as of 2015. The burden of sarcoidosis is changing, with increasing incidence among males in recent years and decreasing disease rates in females. http://bit.ly/2K4WxP5 ER -