TY -的T1 -腔静脉回流和右心室肺动脉高血压的僵硬JF -欧洲呼吸杂志》乔和J - 10.1183/13993003.00625 -2019欧元六世- 54 - 4 SP - 1900625 AU -马库斯,J·蒂姆•AU - Westerhof Berend e . AU - Groeneveldt,乔安妮·a . AU - Bogaard伤害1月非盟-德曼,弗朗西丝·s . AU - Vonk Noordegraaf,安东Y1 - 2019/10/01 UR - //www.qdcxjkg.com/content/54/4/1900625.abstract N2 -腔静脉回流的右心室衰竭是一种常见临床标志肺动脉高血压(PAH)。回流可能导致从三尖瓣返流在右心室收缩或受损的右心室舒张压灌装在心房收缩。我们的目的是量化的向前和向后流腔静脉,建立多环芳烃的主要原因。62年PAH患者心脏磁共振测量提供体积流(mL·s−1)上级和下腔静脉;时间集成流的体积。“落后的分数”被定义为向后和向前卷的比率腔静脉,表示为一个百分比。时间的最大腔静脉回流被表示为一个心动周期的百分比。右心室容量和体积测定主动脉中风。右心catheterisation给右心室,右心房压力。右心室舒张末期刚度决心single-beat方法。The median (interquartile range) backward fraction was 12% (3–24%) and it was >20% in 21 patients. Maximum backflow occurred at near 90% of the cardiac cycle, coinciding with atrial contraction. The backward fraction was associated with maximal right atrial pressure (Spearman's r=0.77), right ventricular end-diastolic stiffness (r=0.65) and right ventricular end-diastolic pressure (r=0.77), and was negatively associated with stroke volume (r= –0.61) (all p<0.001).Significant backward flow in the vena cava was observed in a large group of PAH patients and occurred mostly during atrial contraction as a consequence of impaired right ventricular filling due to right ventricular diastolic stiffness. The backward flow due to tricuspid regurgitation was of significance in only a small minority of patients.In 62 patients with pulmonary arterial hypertension, timing of maximal backflow in the vena cava was in late diastole, during the right atrial contraction. The amount of backflow was associated with right ventricular stiffness. Stroke volume was reduced. http://bit.ly/2Y8YKg8 ER -