TY - T1的吸入的防癌效果d corticosteroids in COPD are likely related to modification of epithelial activation JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.01088-2019 VL - 54 IS - 3 SP - 1901088 AU - Soltani, Amir AU - Mahmood, Malik Q. AU - Reid, David W. AU - Walters, E. Haydn Y1 - 2019/09/01 UR - //www.qdcxjkg.com/content/54/3/1901088.abstract N2 - The article published by Raymakers et al. [1] presents a lung cancer-protective effect of inhaled corticosteroids (ICS) in patients with COPD. The authors suggest that this effect is due to “anti-inflammatory” properties of ICS on the airways. This may be partly true but, from what we have come to know of COPD pathogenesis, the situation is likely to be more nuanced and complicated than that.COPD is an independent risk factor for lung cancer. Studies have suggested that inhaled corticostroids have reduced the incidence of lung cancer in these patients. This effect is likely related to modification of epithelial–mesenchymal transition (EMT). http://bit.ly/2Km4VK4 ER -