TY - Jour T1 - 超声弹性成像：差异诊断胸腔积液的新工具JF - 欧洲呼吸杂志Jo - Eur Respir J Do - 10.1183/13993003.02018-2018 VL - 54 IS - 2 SP - 1802018 Au - 江，宾·互惠- Li, Xue-lian AU - Yin, Yan AU - Zhang, Qin AU - Zang, Tong AU - Song, Wang-shu AU - Wang, Xue-mei AU - Kang, Jian AU - Herth, Felix J.F. AU - Hou, Gang Y1 - 2019/08/01 UR - //www.qdcxjkg.com/content/54/2/1802018.abstract N2 - Introduction Traditional thoracic ultrasound (TUS) is often the initial tool used to help diagnose malignant pleural effusion (MPE). Ultrasound elastography, a relatively new technique, has been used to differentiate malignant disease from benign disease by evaluating tissue “stiffness”. However, no studies evaluating the efficacy of ultrasound elastography for diagnosing MPE are available. We assessed the value of ultrasound elsatography for diagnosing MPE prospectively.Methods All 244 enrolled patients were divided into a development set and a validation set in chronological order. The cut-off elasticity index was established using a receiver operating characteristic curve constructed from the continuous data of the patients in the development set. The diagnostic performance of ultrasound elastography was compared with that of TUS in the validation set.Results In the development set, the mean elasticity index (47.25 kPa) was the optimal cut-off. In the validation set, pleural ultrasound elastography had a sensitivity of 83.64%, a specificity of 90.67%, a positive predictive value of 86.79%, a negative predictive value of 88.31%, a positive likelihood ratio of 8.96 and a negative likelihood ratio of 0.18 for diagnosing MPE. The sensitivity of ultrasound elastography was significantly higher (p=0.006) than that of TUS (60%).Conclusion Pleural ultrasound elastography is a better technique than TUS for differentiating MPE from benign pleural disease.Pleural ultrasound elastography is a better technique than traditional thoracic ultrasound for diagnosing malignant pleural effusion http://bit.ly/2VX4Qns ER -