Ty-Jour T1 - 当“B”变为“A”时：流感的新兴威胁B病毒JF - 欧洲呼吸期刊Jo - Eur Respir J Do - 10.11.01325-2019 VL - 54是 - 2 SP - 1901325 Au - Sharma，Lokesh Au - Rebaza，Andre Au - Dela Cruz，Charles S. Y1 - 2019/08/01 UR - //www.qdcxjkg.com/content/54/2/1901325.abstract n2 - 流感病毒（流感）1918年引起最严重的疾病介导的造成造成的毁灭，当时全球死亡估计为50％至1亿人[1]。由于我们对疾病的理解以及疫苗和抗病毒剂的可用性，流感每年不会杀死更多人，并且在致病性和疫苗和抗病毒药物的可用性方面没有明显降低。去年，仅估计流感的死亡人数在美国估计为80 000，使其成为最致命的传染病[2]。流感病毒发生的一个明显的变化是流感B菌毒株在多年来疾病的重要贡献者。流感B的起源尚不清楚，但首先将在1940年左右孤立，并在1983年，山形样和维多利亚样菌株中分为两种清晰的谱系[3]。科学和医疗保健社区一直在掌握这一重要事件，与流感A A相比，这种重要事件和流感B已被标记为“B”团队。与一些流感A的菌株（如H3N2）相比，流感B被认为是较温和的病毒。比流感更有效，如H1N1 [4]。事实上，多项研究表明流感B病毒的效力增加了造成严重疾病和死亡率。流感B是每四到五年的最突出的流感循环压力。 Furthermore, influenza B infections carried higher risks of hospitalisations compared to influenza A infections in HIV patients [5]. Similarly, influenza B has been described to have significantly higher mortality rates compared to influenza A strains. For example, during the flu season in 2010–2011, influenza B was responsible for 38% of deaths in the paediatric population. National Respiratory and Enteric Virus Surveillance System collaborating laboratories indicated that only 26% of circulating strains of flu were influenza B viruses during this period [6]. Similarly, a Canadian study from 2004 to 2013 found significantly higher mortality rates due to influenza B compared to influenza A in children younger than 16 years of age [7]. These data strongly refute the claims that influenza B is the milder version of the flu. In this issue of the European Respiratory Journal, the study by Bui et al. [8] sheds light on influenza B interactions within the human respiratory tract and lung to demonstrate its pathogenicity and its potential to spread and cause severe lung infections.Influenza B virus can be as virulent as influenza A http://bit.ly/2SnBZ72 ER -