TY - T1的预测心脏手术后谵妄患者的睡眠障碍性呼吸JF -欧洲呼吸杂志》乔和J - 10.1183/13993003.00354 -2019欧元六世- 54 - 2 SP - 1900354 AU Tafelmeier玛丽亚盟——克纳普,马文盟——Lebek西蒙盟——Floerchinger Bernhard盟——Camboni Daniele盟——Creutzenberg马库斯AU -维西格丽德盟,泽曼Florian盟,施密德Christof盟——麦尔,Lars齐格弗里德盟——瓦格纳,Stefan盟——医生,迈克尔Y1 - 2019/08/01 UR - //www.qdcxjkg.com/content/54/2/1900354.abstract N2 -介绍谵妄心脏手术后最常见的并发症之一。虽然已经确定了各种危险因素，但睡眠呼吸障碍(SDB)和谵妄之间的联系迄今为止几乎没有被研究过。在这里，我们的目的是确定术后谵妄的发生率，并确定谵妄的危险因素，有和没有SDB的患者。正在进行的前瞻性观察性研究CONSIDER-AF (ClinicalTrials.gov标识符NCT02877745)对141例心脏手术患者谵妄的危险因素进行了亚分析。术前一晚使用便携式SDB监测仪评估SDB的存在和类型。在拔管当天，在重症监护病房采用有效的混淆评估方法对谵妄进行前瞻性评估，最长持续3天。结果23%的患者诊断为谵妄，16%的无SDB患者诊断为谵妄，13%的患者诊断为阻塞性睡眠呼吸暂停，49%的患者诊断为中枢性睡眠呼吸暂停。多变量logistic回归分析显示谵妄与年龄≥70岁独立相关(OR 5.63, 95% CI 1.79-17.68;p=0.003)、中枢性睡眠呼吸暂停(OR 4.99, 95% CI 1.41-17.69;p=0.013)和心力衰竭(OR 3.3, 95% CI 1.06-10.35; p=0.039). Length of hospital stay and time spent in the intensive care unit/intermediate care setting were significantly longer for patients with delirium.Conclusions Among the established risk factors for delirium, central sleep apnoea was independently associated with delirium. Our findings contribute to identifying patients at high risk of developing post-operative delirium who may benefit from intensified delirium prevention strategies.This prospective observational study shows that, among established risk factors, central sleep apnoea is independently associated with post-operative delirium in patients undergoing elective cardiac surgery http://bit.ly/2LPsrSp ER -