ty -jour t1-肺动脉或慢性血栓栓塞性肺动脉高压患者的住所氧疗法对运动能力和生活质量的影响：一项随机的，安慰剂对照试验JF-欧洲呼吸杂志 -VL -54 IS -2 SP -1900276 Au -Ulrich，Silvia au -Saxer，Stéphanieau -Hasler，Elisabeth D. Au -Schwarz，Esther I. Au I. Au -Schneider，Simon R. Au -Au -furian，Michael Au -Bader，Partick，Partick，Partick，Partick，Partick，Partick，PartickR. au -Lichtblau，Mona au -Bloch，Konrad E. Y1-2019/08/01 UR -http：//www.qdcxjkg.com/content.com/content/54/2/2/1900276.abstract n2-研究问题，我们研究了我们是否研究了Zoniciliary氧疗法（DOXT）增加了肺动脉或远端慢性血栓栓塞性肺动脉高压（PAH/CTEPH）患者的运动能力和生活质量，表现出轻度静息低氧血症和运动诱导的氧气去饱和度。30患者和方法30患者患有PAH/CTEPH，PAH/CTEPH，PAH/CTEPH，PAH/CTEPH。平均±SD年龄60±15岁，PU液态动脉压39±11 mmHg，通过脉搏血氧饱和度（SPO2）≥90％测得的静息动脉氧饱和度，在6分钟步行测试中≥4％的SPO2下降，在肺高血压靶向药物上，以双盲盲随机化分频协议和安慰剂和安慰剂（环境空气）治疗，每次超过5周，在3 l·min -1中通过鼻套管过夜和白天休息。治疗期通过2周的冲洗分离。共同结果是步行6分钟的距离（6MWD，呼吸环境空气）和治疗期间的36项短形式医疗结果问卷的身体功能量表的变化。回升DOXT增加了6MWD，从底线478±113 m增加了6MWD。平均（95％CI）为19（6-32）m，身体功能从52±29乘4（0-8）点。 Corresponding changes with placebo were 1 (−11–13) m in 6MWD and −2 (−6–2) points in physical functioning. Between-treatment differences in changes were 6MWD 18 (1–35) m (p=0.042) and physical functioning 6 (1–11) points (p=0.029). DOXT significantly improved the New York Heart Association functional class versus placebo.Answer to the question This first randomised trial in PAH/CTEPH patients with exercise-induced hypoxaemia demonstrates that DOXT improves exercise capacity, quality of life and functional class. The results support large long-term randomised trials of DOXT in PAH/CTEPH.Domiciliary oxygen therapy improves 6-min walk distance and quality of life in patients with precapillary pulmonary hypertension who desaturate during exercise, and should thus be considered as an adjunct to medical therapy http://bit.ly/2M8H4iq ER -