TY - JOUR T1 -成人非流感呼吸道病毒引起的社区获得性肺炎的疾病严重程度和临床转归:CAP-China网络的多中心前瞻性注册研究摩根富林明-欧洲呼吸杂志》乔和J - 10.1183/13993003.02406 -2018欧元六世- 54 - 2 SP - 1802406 AU -周,范AU -王,伊敏盟——刘Yingmei盟——刘Xuedong AU - Gu,李盟——张Xiaoju AU - Pu, Zenghui AU -杨,Guoru盟——刘,博盟,聂Qingrong盟——雪,Bing盟——冯京盟——郭,羌族非盟- Liu Jianhua AU -风扇,香港非盟-陈,金盟——张,您所想盟——徐Zhenyang盟,庞分盟,陈昱盟,聂Xiuhong AU - Cai,中国非盟-徐,金富AU -彭,库恩AU - Li Xiangxin盟——香,江苏省南通市盟——张Zuoqing盟——江Shujuan AU - Su,鑫盟——张,杰盟- Li Yanming AU -金,Xiuhong盟——江Rongmeng盟——咚,建平盟歌,Yuanlin盟——周,香港非盟-王,陈盟,曹本A2 - Y1 - 2019/08/01 UR - //www.qdcxjkg.com/content/54/2/1802406.abstract N2 -尽管流感病毒性肺炎已经建立的广泛的知识,非流感呼吸道病毒在社区获得性肺炎(CAP)中的意义及其对临床结果的影响尚不清楚，特别是在非免疫功能低下的成年人群中。前瞻性地从中国大陆34家医院招募了具有免疫功能的CAP住院患者。用分子方法检测呼吸道病毒。流感和非流感病毒感染组进行比较。在2336名感染病毒的成年患者中，共有915人被纳入分析，其中流感病毒(28.4%)是最常见的病毒，其次是呼吸道合胞病毒(3.6%)、腺病毒(3.3%)、人类冠状病毒(3.0%)、副流感病毒(2.2%)、人类鼻病毒(1.8%)和人类肺间质病毒(1.5%)。非流感病毒感染占病毒性肺炎的27.4%。腺病毒感染患者更常观察到实变。脓毒症等并发症的发生率(40.1% vs 39.6%; p=0.890) and hypoxaemia (40.1% versus 37.2%; p=0.449) during hospitalisation in the influenza viral infection group did not differ from that of the non-influenza viral infection group. Compared with influenza virus infection, the multivariable adjusted odds ratios of CURB-65 (confusion, urea >7 mmol·L−1, respiratory rate ≥30 breaths·min−1, blood pressure <90 mmHg (systolic) or ≤60 mmHg (diastolic), age ≥65 years) ≥3, arterial oxygen tension/inspiratory oxygen fraction <200 mmHg, and occurrence of sepsis and hypoxaemia for non-influenza respiratory virus infection were 0.87 (95% CI 0.26–2.84), 0.72 (95% CI 0.26–1.98), 1.00 (95% CI 0.63–1.58) and 1.05 (95% CI 0.66–1.65), respectively. The hazard ratio of 90-day mortality was 0.51 (95% CI 0.13–1.91).The high incidence of complications in non-influenza viral pneumonia and similar impact of non-influenza respiratory viruses relative to influenza virus on disease severity and outcomes suggest more attention should be given to CAP caused by non-influenza respiratory viruses.The high incidence of complications in non-influenza viral pneumonia and similar impact of non-influenza viruses relative to influenza virus on disease severity and outcomes suggest more attention should be given to CAP caused by non-influenza viruses http://bit.ly/2vRTvFK ER -