ty -jour t1-高渗盐水吸入的结果作为无链分枝杆菌肺病JF的治疗方式 - 欧洲呼吸杂志Au -Zweijpfenning,Sanne M.H.Au -Pennings,Lian J. Au -Boeree,Martin J.Au -van Ingen,Jakko Au -Magis -Escurra,Cecile Au -Hoefsloot -wouter Y1-2019/07/01 Ur -http://erjourj.ersjournals.com.com/Content/54/1/1802143.Abstract N2-治疗无结核分枝杆菌肺疾病(NTM -PD)对临床医生和患者构成了挑战。治疗涉及18-24个月的多药抗生素疗法,治愈率为50–70%[1]。治疗率取决于因果NTM物种,药物敏感性和疾病表现;大环内酯类抗性和纤维拯救疾病是治疗衰竭的危险因素。即使被认为是成功的治疗,通过复发或重新感染也存在很高的复发风险。此外,经常会看到不良事件,例如胃肠道不适,偶尔需要停用治疗[1]。潜在肺部疾病的治疗对于成功的NTM-PD治疗至关重要[1]。由于高渗盐水(HS)吸入是安全的,并且在支气管扩张患者中显示出临床作用[2-4],因此我们在本地NTM治疗方案中包括HS吸入。 In clinical practice, we advise patients with nodular-bronchiectatic disease to start with HS inhalation two times daily as the only therapy for the first 3 months. When patients tolerate HS and when there are no clinical signs of disease deterioration, we continue HS as the only treatment with close observation of possible disease progression. This clinical observation includes a high-resolution chest tomography, sputum or bronchoalveolar lavage mycobacterial cultures and pulmonary function tests.Patients with nontuberculous mycobacterial lung disease benefit from hypertonic saline inhalation http://bit.ly/2WQpYMz ER -