作者@article {Wijmans1801520 = {Wijmans,丽萃,research,乔伊和熊先生,丹尼尔·m·梅耶尔,Sybren l .先生,保罗和Bonta,彼得•i和Annema Jouke T。},标题= {Needle-based共焦激光endomicroscopy实时诊断~和肺癌的分期},体积= {53}= {6},elocation-id = {1801520} = {2019}, doi ={10.1183/13993003.01520 -2018},出版商={欧洲呼吸学会},文摘={诊断肺癌支气管异常是在缺乏挑战性。188bet官网地址Needle-based共焦激光endomicroscopy (nCLE)使实时细胞显微成像。我们评估的可行性和安全使用nCLE实时识别肺癌。怀疑或证实的肺癌患者安排在内镜超声(欧盟),肺肿瘤和纵隔淋巴结细针穿刺活检前nCLE成像(FNA)。nCLE肺癌特征与病理被比较。多个被评级机构验证CLE肺肿瘤和纵隔淋巴结的视频,两次。EUS-nCLE-FNA在22 ~怀疑或证实的肺癌患者在他27 ~病变(六个肿瘤,纵隔淋巴结21日)进行评估,没有并发症。三个nCLE肺癌标准(暗多形性细胞肿大,黑团和定向流)中被确认。nCLE成像的准确性检测恶性肿瘤在肿瘤和89 \ 90 \ % %在转移性淋巴结。 Both inter-observer agreement (mean κ=0.68, 95\% CI 0.66{\textendash}0.70) and intra-observer agreement (mean{\textpm}sd κ=0.70{\textpm}0.15) were substantial.Real-time lung cancer detection by endosonography-guided nCLE was feasible and safe. Lung cancer characteristics were accurately recognised.Real-time lung cancer detection by endosonography-guided nCLE was feasible and safe. nCLE lung cancer characteristics were accurately recognised. nCLE might become a useful adjunct to bronchoscopy for real-time identification of lung tumours. http://ow.ly/PE7m30o8rSn}, issn = {0903-1936}, URL = {//www.qdcxjkg.com/content/53/6/1801520}, eprint = {//www.qdcxjkg.com/content/53/6/1801520.full.pdf}, journal = {European Respiratory Journal} }