作者@article {Casal1802220 ={有格的,罗伯特·f·Sepesi,鲍里斯和Sagar Ala-Eddin s和Tschirren Juerg和陈,风骚女子和李,梁和阳光,珍妮弗和威廉姆斯,乔伊斯和Grosu Horiana b和Eapen,乔治·a·吉梅内斯,卡洛斯·a .和Ost, David e .}, title ={集中位于肺癌和~神秘节疾病的风险:客观评价肿瘤中心的多个定义专用成像软件},体积= {53}= {5},elocation-id = {1802220} = {2019}, doi ={10.1183/13993003.02220 -2018},出版商={欧洲呼吸学会},文摘={介绍当前的指南建议侵入性纵隔分段集中位于患者影像学阶段T1N0M0 nonsmall细胞性肺癌(NSCLC)。188bet官网地址缺乏中央肿瘤的具体定义导致了指导方针和实践模式的异质性的差异。方法我们的目的是研究肿瘤中心性的具体定义及其与隐匿淋巴结疾病的关系。临床(c) T1N0M0非小细胞肺癌患者的术前胸部计算机断层扫描使用专用软件系统进行处理，该软件系统按照垂直和同心线将肺分为三分。该软件根据肿瘤中心的位置和最内侧的位置，将肿瘤精确地分配到特定的第三个位置，创建了八种可能的中央肿瘤定义。结果607例患者纳入本研究。596例肿瘤接受了手术治疗(98\%)。总体病理(p) N疾病为:504 (83\%)N0, 56 (9\%) N1, 47 (8\%) N2和no N3。无论肿瘤的位置如何，N2期疾病的患病率都相对较低。中心肿瘤与从cN0到任何N (pN1/pN2)的上分期相关。有两种定义与任何N的上分期相关:同心线、内三分之一、肿瘤中心(或3.91,95\% CI 1.85{\textendash}8.26; p\<0.001) and concentric lines, inner two-thirds, most medial aspect of the tumour (OR 1.91, 95\% CI 1.23{\textendash}2.97; p=0.004).Conclusions We objectively identified two specific definitions of central tumours. While the rate of occult mediastinal disease was relatively low regardless of tumour location, central tumours were associated with upstaging from cN0 to any N.In T1N0M0 nonsmall cell lung cancer, the prevalence of occult mediastinal disease is low regardless of tumour location. However, centrally located tumours are at risk of upstaging to any N.~Here, two specific definitions of central tumours are identified. http://ow.ly/pqa130nIokW}, issn = {0903-1936}, URL = {//www.qdcxjkg.com/content/53/5/1802220}, eprint = {//www.qdcxjkg.com/content/53/5/1802220.full.pdf}, journal = {European Respiratory Journal} }