TY -的T1 - < em >击溃或snort sleepe : a detailed medical description of sleep disordered breathing and its consequences by Georg Grau in 1688 JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.01799-2018 VL - 53 IS - 5 SP - 1801799 AU - Rupprecht, Sven AU - Schönefeld, Doris AU - Kroegel, Nasim AU - Witte, Otto W. AU - Schwab, Matthias AU - Paditz, Ekkehart Y1 - 2019/05/01 UR - //www.qdcxjkg.com/content/53/5/1801799.abstract N2 - To date, the description of the excessive sleepiness of “Joe the fat boy” depicted in The Pickwick Papers by Charles Dickens is widely considered to be the first poetical portrayal of sleep disordered breathing (SDB) [1, 2]. The clinical significance of SDB, however, was not recognised until the second half of the 20th century [2, 3]. In Hypnologia, a compendium on sleep written by Georg Grau in 1688, which has recently been rediscovered, the author presents an astonishingly accurate description of a series of symptoms that today can be regarded as portraying a complete picture of SDB and/or the obstructive sleep apnoea syndrome [4]. This compendium will be introduced briefly below.Description of sleep disordered breathing and its consequences was made as early as the 17th century, including upper airway pathology during sleep, risk factors for SDB and medical consequences, simply based on detailed medical observation and examination http://ow.ly/SVRq30o98KV ER -