ty -jour t1-运动和气道通关（正呼气压力）对囊性纤维化中粘液清除的影响：一项随机跨界试验JF-欧洲呼吸杂志JO -EUR RESSIR J DO -10.1183/13993003.01793-2018SP -1801793 Au -Dwyer，Tiffany J. au -Daviskas，Evangelia au -Zainuldin，Rahizan au -Verschuer，Jordan Au -Eberl -Stefan Au -bye -Bye，Peter T.P.Au -Alison，Jennifer A. Y1-2019/04/01 Ur -http：//www.qdcxjkg.com/content/53/4/4/1801793.Abstract N2-锻炼N2-锻炼可改善没有肺部疾病的人的粘液清除，患有慢性疾病的人的粘液清除支气管炎。没有研究单独研究囊性纤维化（CF）中粘液清除的运动。这项研究的目的是比较跑步机运动对静息呼吸和气道的影响，并具有正呼气压力（PEP）疗法对CF成人的粘液清除率。严重的CF肺部疾病（1％的强迫呼气量预测31-113％）。干预措施为20分钟的静息呼吸（对照），跑步机运动的60％，占参与者的峰值消耗量或PEP治疗（包括Huffing和咳嗽）。使用放射性胶质技术和伽马摄像头成像测量粘液清除率。与静息呼吸相比，Streadmill运动改善了整个肺粘液清除率（平均差异为3％，95％CI 2-4）；然而，仅运动的效率不如PEP治疗（平均差异-7％，95％CI -6- −8）。 When comparing treadmill exercise to PEP therapy, there were no significant differences in mucus clearance from the intermediate and peripheral lung regions, but significantly less clearance from the central lung region (likely reflecting the huffing and coughing that was only in PEP therapy).It is recommended that huffing and coughing are included to maximise mucus clearance with exercise.Exercise and PEP therapy significantly improve mucus clearance in CF, but PEP therapy clears more mucus than exercise alone http://ow.ly/d7j530nvUOM ER -