TY -的T1 -呼出空气分散在高速流鼻插管治疗< em >和< / em > CPAP通过< / em > < em >不同面具JF -欧洲呼吸杂志》乔和J - 10.1183/13993003.02339 -2018欧元六世- 53 - 4 SP - 1802339 AU -回族,David s . AU - Chow,本尼k . AU - Lo,托马斯盟——曾荫权,欧文T.Y. AU - Ko,范妮w . AU - Ng,苏珊娜s . AU -杜松子酒,托尼AU - Chan)背景高流量鼻插管(HFNC)是一种新兴的治疗呼吸衰竭的方法，但治疗过程中呼出气体的分散程度尚不清楚。我们在隔离室进行了16次换气·h−1的人体病人模拟器(HPS)上，研究了HFNC治疗与持续气道正压(CPAP)治疗期间呼出的空气分散情况。方法将HPS编程代表不同程度的肺损伤。CPAP以5-20 cmH2O通过鼻枕(呼吸学Nuance Pro Gel或ResMed Swift FX)或口鼻口罩(ResMed Quattro Air)进行。加湿至37°C的HFNC，以10-60 L·min−1的速度输送至HPS。呼出的气流用肺内烟雾标记，以便可视，并用激光光片显示。从烟雾粒子散射的光中估计出归一化呼出空气浓度。当归一化烟雾浓度≥20%时，即为显著暴露。结果在正常肺条件下，使用respiratory onics和ResMed鼻枕将CPAP从5 cmH2O增加到20 cmH2O时，沿矢状面平均±sd呼出气体弥散量由186±34 mm增加到264±27 mm，由207±11 mm增加到332±34 mm。口鼻面罩的渗漏可以忽略不计。 Mean±sd exhaled air distances increased from 65±15 to 172±33 mm when HFNC was increased from 10 to 60 L·min−1. Air leakage to 620 mm occurred laterally when HFNC and the interface tube became loose.Conclusion Exhaled air dispersion during HFNC and CPAP via different interfaces is limited provided there is good mask interface fitting.Exhaled air dispersion from high-flow nasal cannula (HFNC) and CPAP is limited provided there is good mask interface fitting. However, exhaled air leakage to 620 mm laterally occurs when the connection between HFNC and the interface tube becomes loose. http://ow.ly/lqEF30nqjq6 ER -