@article {Crombag1800800作者={劳伦斯M.M. Crombag克利斯朵夫注定和乔斯a Stigt和库尔特·g·Tournoy奥尔加C.J. Schuurbiers Maarten k . Ninaber Wieneke a Buikhuisen和赛义德~硕士Hashemi和彼得。Bonta达尼{\“e} l a Korevaar和Jouke ~ T。Annema},标题={系统并结合endosonographic肺癌的分期研究(得分)},体积= {53}= {2},elocation-id = {1800800} = {2019}, doi ={10.1183/13993003.00800 -2018},出版商={欧洲呼吸学会},文摘={指南推荐endosonography纵隔淋巴结分期可切除的患者nonsmall细胞性肺癌(NSCLC)。188bet官网地址我们假设系统支气管内超声(欧洲)评价结合食管调查使用相同的如支气管镜(EUS-B)提高纵隔淋巴结分期与当前的实践有针对性的正电子发射断层扫描(PET)计算断层扫描(CT)引导欧洲举办。前瞻性、多中心、国际研究(NCT02014324)是在连续进行的(疑似)切除的非小细胞肺癌患者。pet - ct机后,病人接受了系统如和EUS-B。节点(s)可疑CT、PET、欧洲和/或EUS-B成像和站4 r, l 4和7(短轴> = 8毫米)取样。对病人没有N2和N3疾病决心endosonography surgical-pathological分期是参考标准。229名患者纳入本研究。N2和N3疾病的患病率是103年的229例(45 \ %)。PET-CT-guided有针对性的方法,如确定75 N2和N3疾病患者(灵敏度73 \ %、95 \ % CI 63 {\ textendash} 81 \ %;阴性预测值(NPV) 81 \ %, 95 \ % CI 74 {\ textendash} 87 \ %)。 Four additional patients with N2/N3 disease were found by systematic EBUS (sensitivity 77\%, 95\% CI 67{\textendash}84\%; NPV 84\%, 95\% CI 76{\textendash}89\%) and five more by EUS-B (84 patients total; sensitivity 82\%, 95\% CI 72{\textendash}88\%; NPV 87\%, 95\% CI 80{\textendash}91\%). Additional clinical relevant staging information was obtained in 23 out of 229 patients (10\%).Systematic EBUS followed by EUS-B increased sensitivity for the detection of N2/N3 disease by 9\% compared to PET-CT-targeted EBUS alone.In lung cancer patients, a systematic endobronchial ultrasound (EBUS) combined with an oesophageal investigation using the same EBUS bronchoscope (EUS-B) increases the sensitivity for mediastinal nodal staging by 9\% compared to a targeted EBUS procedure http://ow.ly/aPqF30mJ15q}, issn = {0903-1936}, URL = {//www.qdcxjkg.com/content/53/2/1800800}, eprint = {//www.qdcxjkg.com/content/53/2/1800800.full.pdf}, journal = {European Respiratory Journal} }