诺兰，Claire M.和Maddocks, Matthew和Maher, Toby M.和Banya, Winston和Patel, Suhani和Barker, Ruth E.和Jones, Sarah E.和George, Peter M.和Cullinan, Paul和Man, William D-C。},标题={步态速度和特发性肺纤维化患者的预后:前瞻性队列研究},体积= {53}= {2},elocation-id = {1801186} = {2019}, doi ={10.1183/13993003.01186 -2018},出版商={欧洲呼吸学会},文摘= {4 m步态速度(4毫克),一个简单的物理性能测量和代理脆弱的标志,一直预测老年人不良预后。188bet官网地址我们假设4mg可以预测特发性肺纤维化(IPF)患者的全因死亡率和非选择性住院。对130例新诊断为IPF的门诊患者在基线时测量4mg和肺功能。生存状况和非选择性住院记录超过1年。我们评估了4mg的预测值(作为连续变量和二元变量:慢的4mg与保留的4mg)，方法是使用Cox比例回归计算风险比，并调整潜在的混杂变量。受试者工作特征曲线评估了多变量回归模型和已建立的预后指标之间的差别。持续4mg和缓慢4mg是全因死亡的独立预测因子(4mg: HR 0.03, 95\% CI 0.01{\textendash}0.31;p = 0.004;慢速4mg: 2.63, 95\% CI 1.01{\textendash}6.87;p=0.049)和住院治疗(4mg: HR 0.02, 95\% CI 0.01{\textendash}0.14;p \ < 0.001; slow 4MGS: 2.76, 95\% CI 1.16{\textendash}6.58; p=0.02). Multivariable models incorporating 4MGS or slow 4MGS had better discrimination for predicting mortality than either the gender, age and lung physiology index or Composite Physiologic Index.In patients with IPF, 4MGS is an independent predictor of all-cause mortality and nonelective hospitalisation.4MGS independently predicts all-cause mortality and nonelective hospitalisation in patients with newly diagnosed IPF http://ow.ly/cT9H30mCkUr}, issn = {0903-1936}, URL = {//www.qdcxjkg.com/content/53/2/1801186}, eprint = {//www.qdcxjkg.com/content/53/2/1801186.full.pdf}, journal = {European Respiratory Journal} }