%0期刊文章%contreras,Zuelma A.%A chen,Zhanghua%A roumeliotaki,Theano%Annesi-Maesano,Isabella%abaïz,nour%von a a von berg,andrea a andrea%abergströmduijts,liesbeth%aekström,sandra%a eller,esben%a fantini,玛丽亚·P·%a kjaer,henrik fomsgaard%a forastiere a forastiere,francesco%a gerhard,beattrix%a gori a gori a gori,davide%a harskamp-van ginkingel,harskamp-van ginkingel,margingel,margret,margretW.%A Heinrich,Joachim%AIñiguez,Carmen%A Inskip,Hazel%A Keil,Thomas%A KOGEVINAS,MANOLIS%A lau,Susanne%A Lehmann,Irina%A Maier,Dieter%A van Meel,Van Meel,Evelien R.,Evelien R.,Evelien R.%a妈妈,monique%a murcia,mario%a porta,daniela%a smit,henriëtteA。%a stantl,marie%a stratakis,nikos a stratakis,nikos%a sunyer,jordi%a thijs a thijs,carel%torrent a torrent,maties%a vrijkotte a vrijkotte a vrijkotte a vrijkotte,Tanja G.M.%wijga,Alet H.%A Berhane,Kiros%A Gilliland,Frank%Chatzi,Leda%T会早期发作会增加儿童肥胖风险吗?对16个欧洲队列%d 2018%r 10.1183/13993003.00504-2018%J欧洲呼吸期杂志%p 1800504%v 52%n 3%x童年哮喘和肥胖症的平行流行性研究在过去几十年中迅速研究,对16%的欧洲队列的合并分析r 10.1183/13993003.00504-2018%j肥胖是哮喘的危险因素。但是,关于哮喘在肥胖发生率中的作用知之甚少。我们检查了早期发作的哮喘和相关表型是否与童年发展肥胖的风险有关。这项研究包括1990年至2008年在丹麦,法国,德国,希腊,意大利,荷兰,西班牙,瑞典,瑞典和瑞典,瑞典和瑞典,瑞典和瑞典,瑞典和2008年出生的21个130名儿童英国。 We followed non-obese children at 3–4 years of age for incident obesity up to 8 years of age. Physician-diagnosed asthma, wheezing and allergic rhinitis were assessed up to 3–4 years of age.Children with physician-diagnosed asthma had a higher risk for incident obesity than those without asthma (adjusted hazard ratio (aHR) 1.66, 95% CI 1.18–2.33). Children with active asthma (wheeze in the last 12 months and physician-diagnosed asthma) exhibited a higher risk for obesity (aHR 1.98, 95% CI 1.31–3.00) than those without wheeze and asthma. Persistent wheezing was associated with increased risk for incident obesity compared to never wheezers (aHR 1.51, 95% CI 1.08–2.09).Early-onset asthma and wheezing may contribute to an increased risk of developing obesity in later childhood.Children who have asthma or wheezing in early childhood may be at a higher risk of developing obesity http://ow.ly/HfKw30lhF3X %U //www.qdcxjkg.com/content/erj/52/3/1800504.full.pdf