@Article {Thille1702465，作者= {Thille，Arnaud W.和Reynaud，Faustine和Marie，Damien和Barrau，St {\'E} Phanie和Rousseau，Ludivine和Rault，Christophe和Diaz，v {\'e} ronique和Meureice，Jean-Claude和Coustoy，R {\'e} MI和Frat，Jean-Pierre和Robert，Ren {\'e}和Drouot，Xavier}，标题= {睡眠改变对机械通风患者的断奶持续时间的影响：一个潜在的研究}，卷= {51}，number = {4}，Elocation-Id = {1702465}，年= {2018}，DOI = {10.1183 / 13993003.02465-2017}，出版商= {欧洲呼吸协会}，188bet官网地址摘要= {睡眠在重症监护室（ICU）患者中显着改变，可能会改变呼吸表现。我们的目标是评估睡眠变化对断奶持续时间的影响。我们在法国教学医院进行了一项潜在的生理学研究。ICU患者预热至少24小时并且难以断奶。完成的PolysomNographic（PSG）在第一次自发呼吸试验失败后进行。通过神经科医生评估眼睛的非典型睡眠，睡眠阶段的持续时间，特别是快速的眼球运动（REM）睡眠和脑电图（EEG）反应性，45名患者中的45名患者（44 \％）有非典型睡眠不根据标准标准进行分类。非典型睡眠患者（中位数（四分位数）5（2 {\ TextEndash} 8）与2（1 {\ TextEndash} 2）天; P = 0.001）和那些人之间的断奶持续时间明显更长与其他人没有睡眠。 Using multivariate logistic regression analysis, atypical sleep remained independently associated with prolonged weaning (\>48 h after PSG). Altered EEG reactivity at eyes opening was a good predictor of atypical sleep.Our results suggest for the first time that brain dysfunction may have an influence on the ability to breathe spontaneously.ICU patients under mechanical ventilation with altered sleep had markedly longer weaning duration than did others http://ow.ly/BJip30jjag5}, issn = {0903-1936}, URL = {//www.qdcxjkg.com/content/51/4/1702465}, eprint = {//www.qdcxjkg.com/content/51/4/1702465.full.pdf}, journal = {European Respiratory Journal} }