A Carder, Melanie %A Darnton, Andrew %A Gittins, Matthew %A Stocks, S. Jill %A Ross, David %A Barber, Chris M. A Agius, Raymond M. T胸科医生报告，工作相关，英国目前的长潜伏期呼吸系统疾病(LLRD)的很大一部分负担归因于历史上的石棉暴露。然而，持续接触其他物质，尤其是二氧化硅，也会增加疾病负担。本研究的目的是调查英国胸科医生报告的与工作有关的LLRD的发生率，包括年龄、性别、职业和可疑因素的变化。估计了1996-2014年各职业的LLRD发病率和发病率比率。按职业划分的间皮瘤病例与死亡率比例进行比较。病例主要是男性(95%)，92%的病例归因于石棉。年平均发病率(男性)每10万人:良性胸膜疾病，7.1 (95% CI 6.0-8.2);间皮瘤,5.4 (4.8 - -6.0);尘肺病,1.9 (1.7 - -2.2);肺癌，0.8 (0.6-1.0); chronic obstructive pulmonary disease (COPD), 0.3 (0.2–0.4). Occupations with a particularly high incidence of LLRD were miners and quarrymen (COPD), plumbers and gas fitters (asbestosis), and shipyard and dock workers (all other categories). There was a clear concordance between cases of SWORD mesothelioma and proportional mortality ratios by occupation.Occupationally caused LLRD continues to contribute to a significant disease burden. Many cases are attributable to past exposure to agents such as asbestos and silica, but the potential for occupational exposures persists.Occupational long-latency respiratory disease contributes to a significant disease burden with ongoing exposure risk http://ow.ly/ahyF30gM9DK %U //www.qdcxjkg.com/content/erj/50/6/1700961.full.pdf