ty -jour t1-临床N1临床N1非小细胞肺癌的视频末期术进行了纵隔分阶段:一项前瞻性多中心研究JF-欧洲呼吸杂志-DeCaluwé,Herbert au -Dooms,Christophe au -d'Journo,Xavier Benoit au-呼叫,Sergi au -Sanchez,David Au -Haager -Haager,Benedikt au -Beelen,beelen,Roel Au -Kara -Kara,Volkan au -Klikovits,Thomas au -klikovits,Thomas au -au -au -auignigneign -auignigneign -auignign,Clemens au -Tournoy,Kurt au -Zahin,Mahmood au -Moons,Johnny au -Brioude,Geoffrey au -Trujillo,Juan Carlos Au -Klepetko- Klepetko,Walter Au -Turna,Turna,Akif Au -Passlick au -passlick au -passlick au -passlick au -passlick au -molins au -molins,laureano,laureano au -laureano,laureano au--Rami -Porta,Ramon au -Thomas,Pascal au -Leyn,Paul de Y1-2017/12/01 Ur -http://www.qdcxjkg.com/content.com/content/50/6/6/1701493.Abstract N2-二分之一的患者基于临床N1(CN1)非小细胞肺癌(NSCLC),基于正电子发射断层扫描 - 分配层析成像(PET-CT)成像具有神秘的纵隔淋巴结受累(N2)疾病)。在一项前瞻性研究中,仅内部摄影术在检测N2疾病方面具有不令人满意的敏感性(38%)。The current prospective multicentre trial investigated the sensitivity of preoperative mediastinal staging by video-assisted mediastinoscopy (VAM) or VAM-lymphadenectomy (VAMLA).Consecutive patients with operable and resectable (suspected) NSCLC and cN1 after PET-CT imaging underwent VAM(LA)。主要研究结果是对检测N2疾病的敏感性。次要终点是N2疾病的患病率,阴性预测值(NPV)和VAM的准确性(LA)。105例CN1患者在影像学上的患者最终患有N2疾病。 Invasive mediastinal staging with VAM(LA) had a sensitivity of 73% to detect N2 disease. The NPV was 92% and accuracy 93%. Median number of assessed lymph node stations during VAM(LA) was 4 (IQR 3–5), and in 96%, at least three stations were assessed.VAM(LA) has a satisfactory sensitivity of 73% to detect mediastinal nodal disease in cN1 lung cancer, and could be the technique of choice for pre-resection mediastinal lymph node assessment in this patient group with a one in four chance of occult-positive mediastinal nodes after negative PET-CT.Videomediastinoscopy reaches a sensitivity of 73% detecting N2 disease in cN1 NSCLC patients; N2 prevalence is 26% http://ow.ly/VrzL30gIOWm ER -