TY - JOUR T1 -自动versus手动氧气管理在急诊科JF -欧洲呼吸杂志JO - Eur Respir J DO - 10.1183/13993003.02552-2016 VL - 50 IS - 1 SP - 1602552 AU - L'Her, Erwan AU - Dias, Patricia AU - Gouillou, Maelenn AU - Riou, Anne AU - Souquiere, Luc AU - Paleiron, Nicolas AU - Archambault, Patrick AU - Bouchard, Pierre-Alexandre AU - Lellouche，François Y1 - 2017/07/01 UR - //www.qdcxjkg.com/content/50/1/1602552.abstract N2 -医院通常使用氧气，对治疗建议的依从性较差。我们对入院需要O2≥3 L·min−1的急诊科患者进行了多中心随机对照研究。患者在3小时内随机接受自动闭环或手动氧气滴定。根据动脉二氧化碳张力(PaCO2)对患者进行分层(低氧时PaCO2≤45mmhg;或高碳酸PaCO2>45 -≤55 mmHg)和研究中心。通过脉搏血氧饱和度(SpO2)测量的动脉氧饱和度，低氧血症患者为92-96%，高碳酸血症患者为88-92%。主要结局为%时间达到SpO2目标。次要终点为低氧血症和高氧发生率、氧气断奶、氧气持续时间和住院时间。187例患者随机分组(93例自动分组，94例手动分组)，各组间基线特征相似。自动滴定法达到SpO2目标的时间更长(81±21% vs 51±30%，p<0.001)。 Time with hypoxaemia (3±9% versus 5±12%, p=0.04) and hyperoxia under O2 (4±9% versus 22±30%, p<0.001) were lower with automated titration. O2 could be weaned at the end of the study in 14.1% versus 4.3% patients in the automated and manual titration group, respectively (p<0.001). O2 duration during the hospital stay was significantly reduced (5.6±5.4 versus 7.1±6.3 days, p=0.002).Automated O2 titration in the emergency department improved oxygenation parameters and adherence to guidelines, with potential clinical benefits.Automated oxygen titration is superior to manual administration in terms of time within oxygenation targets http://ow.ly/pgWC30c2sLv ER -