TY - JOUR T1 -在出生一年内母乳喂养、母亲哮喘和喘息:纵向出生队列研究摩根富林明-欧洲呼吸杂志》乔和J - 10.1183/13993003.02019 -2016欧元六世- 49 - 5 SP - 1602019 AU Azad梅根·b·AU - Vehling罗瑞拉盟- Lu, Zihang AU -戴,大卫盟,苏巴拉奥Padmaja AU -贝克尔,艾伦•b . AU - Mandhane Piushkumar J . AU -特维,斯图尔特•e . AU - LefebvreDiana L. AU - Sears, Malcolm R. Y1 - 2017/05/01 UR - //www.qdcxjkg.com/content/49/5/1602019.abstract N2 -母乳喂养对呼吸道健康的影响尚不确定，尤其是当母亲患有哮喘时。我们研究了母乳喂养和一岁前哮喘之间的关系。我们研究了来自加拿大健康婴儿纵向发展(CHILD)出生队列的2773名婴儿。护理人员报告了3个月、6个月和12个月时婴儿喂养和喘息发作的情况。母乳喂养分为纯母乳喂养、部分母乳喂养(辅以配方奶粉或补充食品)和不母乳喂养。总体而言，21%的母亲有哮喘，46%母乳喂养至少12个月，21%的婴儿有哮喘。在有哮喘的母亲中，母乳喂养与婴儿哮喘呈负相关，且不受母亲吸烟、教育和其他危险因素的影响(校正率比(aRR) 0.52;95% CI 0.35-0.77，母乳喂养≥12个月与6个月)。 Compared with no breastfeeding at 6 months, wheezing was reduced by 62% with exclusive breastfeeding (aRR 0.38; 95% CI 0.20–0.71) and by 37% with partial breastfeeding supplemented with complementary foods (aRR 0.63; 95% CI 0.43–0.93); however, breastfeeding was not significantly protective when supplemented with formula (aRR 0.89; 95% CI 0.61–1.30). Associations were not significant in the absence of maternal asthma (p-value for interaction <0.01).Breastfeeding appears to confer protection against wheezing in a dose-dependent manner among infants born to mothers with asthma.When mums with asthma #breastfeed longer, their babies are less likely to wheezehttp://ow.ly/KWEk3089ZEn ER -