RT期刊论文SR电子T1 ERS支气管激发试验技术标准：一般考虑和乙酰甲胆碱激发的性能测试JF欧洲呼吸杂志JO欧元呼吸杂志FD欧洲呼吸学会SP 1601526 DO 10.1183 / 13993003.01526-2016 VO 49 5个A1科茨，艾伦188bet官网地址L. A1望尔，杰克A1克罗夫特，唐纳德·卡尔弗A1，布鲁斯H. A1，A1卡尔森，凯哈康A1钻石，苏珊娜A1 Gauvreau，盖尔A1馆，格雷厄姆L. A1 Hallstrand，蒂尔S. A1霍瓦特，ILDIKOA1 de Jongh, Frans H.C. A1 Joos, Guy A1 Kaminsky, David A. A1 Laube, Beth L. A1 Leuppi, Joerg D. A1 Sterk, Peter J. YR 2017 UL //www.qdcxjkg.com/content/49/5/1601526.abstract AB This international task force report updates general considerations for bronchial challenge testing and the performance of the methacholine challenge test. There are notable changes from prior recommendations in order to accommodate newer delivery devices. Rather than basing the test result upon a methacholine concentration (provocative concentration (PC20) causing a 20% fall in forced expiratory volume in 1 s (FEV1)), the new recommendations base the result upon the delivered dose of methacholine causing a 20% fall in FEV1 (provocative dose (PD20)). This end-point allows comparable results from different devices or protocols, thus any suitable nebuliser or dosimeter may be used, so long as the delivery characteristics are known. Inhalation may be by tidal breathing using a breath-actuated or continuous nebuliser for 1 min (or more), or by a dosimeter with a suitable breath count. Tests requiring maximal inhalations to total lung capacity are not recommended because the bronchoprotective effect of a deep breath reduces the sensitivity of the test.The new ERS recommendation for methacholine challenge tests will be the provocative dose rather than concentration http://ow.ly/FBe5309yXn2