TY - T1的肺容积预测慢性肺部同种异体移植物功能障碍患者的生存期JF -欧洲呼吸杂志》乔和J - 10.1183/13993003.01315 -2016欧元六世- 49 - 4 SP - 1601315 AU -尼古拉斯Kneidinger AU -凯特琳Milger AU - Silke Janitza AU - Felix Ceelen盟加芙Leuschner AU -朱利安斯佩耳特小麦盟梅勒妮Konigshoff AU -托马斯Weig AU -雷内·施拉姆盟Hauke冬天AU -尤尔根•贝赫盟老人Neurohr Y1 - 2017/04/01 UR - //www.qdcxjkg.com/content/49/4/1601315.abstract N2 -识别疾病的表型可能改善慢性肺移植患者的理解障碍(复合)。这项研究的目的是评估的影响限制肺肺容积测量和困气的复合。共有396个双边肺移植受者进行分析。包在发作,进一步基于体积描记法的范畴。限制性的复合(R-CLAD)被定义为从基线肺活量的丧失。包层与空气捕获(AT-CLAD)被定义为一个残余体积比肺活量增加。结果复合发病后生存。患者临床信息不足被排除在外(n = 95)。301肺移植受者,94(31.2%)开发的复合。患者R-CLAD (n = 20)和AT-CLAD (n = 21),分别有一个明显恶化的生存(术中;0.001)比模拟/ AT-CLAD患者。R-CLAD和AT-CLAD都与死亡率增加有关,当控制多个混杂变量(风险比(人力资源)3.57,95%可信区间1.39 - -9.18;p = 0.008; and HR 2.65, 95% CI 1.05–6.68; p=0.039). Furthermore, measurement of lung volumes was useful to identify patients with combined phenotypes.Measurement of lung volumes in the long-term follow-up of lung transplant recipients allows the identification of patients who are at risk for worse outcome and warrant special consideration.Measurement of lung volumes in lung transplant recipients allows identification of patients at risk of poor outcome http://ow.ly/FCzy3084Al2 ER -