急性肺栓塞后慢性血栓栓塞性肺动脉高压的发生率:发表文献的当代观点JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP 1601792188bet官网地址 DO 10.1181 /13993003.01792-2016 VO 49 IS 2 A1 Ende-Verhaar, Yvonne M. A1 Cannegieter, Suzanne C. A1 Vonk Noordegraaf, Anton A1 Delcroix, Marion A1 Pruszczyk, Piotr A1 Mairuhu, Albert T.A. A1 Huisman, Menno V. A1 Klok，Frederikus A. YR 2017 UL //www.qdcxjkg.com/content/49/2/1601792.abstract AB肺栓塞(PE)后慢性血栓栓塞性肺动脉高压(CTEPH)的发生率与管理决策相关，但目前尚不清楚。我们对包括连续PE患者随访的CTEPH进行了meta分析。研究队列被预先定义为“所有患者”、“幸存者”或“无重大共病的幸存者”。使用随机效应模型计算CTEPH发病率。我们选择了16项研究，共4047名PE患者，他们大多随访2年。在1186名所有患者(两项研究)中，CTEPH的合并发生率为0.56% (95% CI 0.1-1.0)。999名幸存者中(四项研究)CTEPH发生率为3.2% (95% CI 2.0-4.4)。在1775例无主要合并症的幸存者中(9项研究)，CTEPH发生率为2.8% (95% CI 1.5-4.1)。复发性静脉血栓栓塞和无端PE均与较高的CTEPH风险显著相关，优势比分别为3.2 (95% CI 1.7-5.9)和4.1 (95% CI 2.1-8.2)。 The pooled CTEPH incidence in 12 studies that did not use right heart catheterisation as the diagnostic standard was 6.3% (95% CI 4.1–8.4).The 0.56% incidence in the all-comer group probably provides the best reflection of the incidence of CTEPH after PE on the population level. The ∼3% incidences in the survivor categories may be more relevant for daily clinical practice. Studies that assessed CTEPH diagnosis by tests other than right heart catheterisation provide overestimated CTEPH incidences.The incidence of CTEPH is 0.56% in all comers and ∼3% in survivors of acute pulmonary embolism http://ow.ly/PVEh306iNoD