RT Journal Article SR Electronic T1 Growth trajectories and asthma/rhinitis in children: a longitudinal study in Taiwan JF European Respiratory Journal JO Eur Respir J FD 188bet官网地址European Respiratory Society SP 1600741 DO 10.1183/13993003.00741-2016 VO 49 IS 1 A1 Chen, Yang-ChingA1 Liou,Tsan-Hon A1 Chen,Pau-Chung A1 Chiang,Bor-Luen A1 Yang,Yao-Hsu A1粉丝,Hsien-yu A1 Lee,Yungling Leo YR 2017 UL //www.qdcxjkg.com/content/49/1 / 1600741.Abstract AB研究报告了体重在哮喘早期的体重效果。然而,尚未探索生长模式在学龄和鼻炎期间生长模式的影响。我们试图调查各种增长模式是否预测入射哮喘和鼻炎。我们在14个台湾社区进行了全国范围的纵向研究(台湾儿童健康研究)。每年收集4422岁6-11岁儿童的体重指数(BMI)Z分数,并使用潜在的广义混合物模型确定了不同的生长轨迹类。还测量肺功能和呼出的一氧化氮分数(FENO)水平。不同的生长轨迹类别是否预测发生事件哮喘和鼻炎,使用离散时间危险模型确定了15和18岁。鉴定了生长轨迹课程。持续超重的儿童在12年内显着提高了哮喘和鼻炎的风险。此外,持续超重对事件哮喘(危险比2.47,95%CI 1.18-5.12)和鼻炎(危害比1.44,95%CI 1.12-1.84)的长期影响。高BMI课程的儿童与正常生长儿童相比,肺功能显着降低。 FeNO levels were lower in children in the high BMI classes and higher in children showing declining obesity compared with normal growth children.Persistently overweight children exhibited incident asthma and rhinitis in adolescence and early adulthood.Persistently overweight children had a long-term risk of incident asthma and rhinitis in late adolescence http://ow.ly/Ixay3049PYL