AU - McDonald, Fiona AU - De Waele, Michèle AU - Hendriks, Lizza E. L. AU - Faivre-Finn, Corinne AU - Dingemans, Anne-Marie C. AU - Van Schil，Paul e . TI -管理阶段I和II nonsmall细胞肺癌援助- 10.1183/13993003.00764 -2016 DP - 2017年1月01 TA -欧洲呼吸杂志》第六PG - 1600764 - 49 IP - 1 4099 - //www.qdcxjkg.com/content/49/1/1600764.short 4100 - //www.qdcxjkg.com/content/49/1/1600764.full所以欧元和J2017 1月01;49 AB - I期和II期非小细胞肺癌的发病率可能会随着人口老龄化和高危个体筛查的引入而增加。优化管理需要多学科协作。局部治疗包括手术和放疗，目前在特定病例中联合辅助化疗以改善长期疗效。靶向治疗和免疫治疗也可能成为这类患者的重要治疗方式。对于心肺风险低的可切除疾病，完全手术切除肺叶切除术仍是金标准。微创技术，保守和叶下切除术适合一部分患者。有数据显示，放射治疗，特别是立体定向体放射治疗，是一种有效的替代方案，对于有手术风险的患者来说。这是否也适用于好的手术候选人，还有待于随机试验的评估。 In specific subgroups adjuvant chemotherapy has been shown to prolong survival; however, patient selection remains important. Neoadjuvant chemotherapy may yield similar results as adjuvant chemotherapy. The role of targeted therapies and immunotherapy in early stage nonsmall cell lung cancer has not yet been determined and results of randomised trials are awaited.Early stage lung cancer treatment needs multidisciplinary cooperation between physicians, oncologists and surgeons http://ow.ly/EKxe304XhMR