ty -jour t1-引入13个价值的肺炎球菌偶联疫苗在孤立的肺炎球菌疫苗中，没有土著人口JF-欧洲呼吸杂志JO -eur Respir J SP -1492 LP -1492 LP -1496 do -10.1183/139993003.0033003.0089909090-200-2016 VL-488888888888888888880-5 Au -Verhagen，Lilly M. Au -Rivera -Olivero，Ismar A. Au -Hermen，Meyke au -Sisco -Sisco，MaríaCarolinaau -Maes，Mailis au -del Nogal，Berenice au -berenice au -berenice au -bogaert，debby au -au au -berbers，berbers，berbers，guy，berbers，guy，guy，berbers，guy，guy，guy of au -berbers，guy，berbers，guy，guy，berbers，guy of是。AU-赫曼人，彼得·W.M.Au -de Jonge，Marien I. Au -de Waard，Jacobus H. Y1-2016/11/01 ur -http：//www.qdcxjkg.com/content.com/content/48/5/1492.Abstract N2-共轭疫苗（PCV）对受肺炎球菌和疾病影响最大的人群的影响最大，例如土著儿童[1]。尽管约有10％的南美人口由居住在偏远环境中的土著人民组成，但据我们所知，在南美土著儿童中尚未评估PCV。沃拉人是居住在委内瑞拉奥里诺科河三角洲的木制房屋中的美洲印第安人人口。几乎三分之一的沃雅儿童在童年时期死亡，呼吸道感染是死亡的主要原因[2]。这项研究是第一个评估13个价值（PCV13）疫苗接种对鼻咽定植率和抗体反应的影响，对PCV-NOTHE的南美儿童的抗体反应。PCV13对≥24个月的儿童追捕方案可能需要多于超过24个月。 one vaccine dose http://ow.ly/lstI3023i2RThe authors thank the participating families and the field workers involved in the recruitment and sampling of children, in particular the medical students of the Escuela de Medicina José Maria Vargas of the Universidad Central de Venezuela and Thor Küchler, Marcella Overeem and Stèphan Kraai (Laboratorio de Tuberculosis, Instituto de Biomedicina, Universidad Central de Venezuela, Caracas, Venezuela and Laboratory of Paediatric Infectious Diseases, Dept of Paediatrics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Centre, Nijmegen, the Netherlands). Furthermore, we thank Jochem Burghouts (Laboratorio de Tuberculosis, Instituto de Biomedicina, Universidad Central de Venezuela and Laboratory of Paediatric Infectious Diseases, Dept of Paediatrics, Radboud Institute for Molecular Life Sciences) for facilitation of study logistics. At the RIVM (National Institute for Health and Environment, Bilthoven, the Netherlands), we thank Irina Tcherniaeva for technical support. We are grateful to the personnel of the Laboratorio de Tuberculosis, Instituto de Biomedicina (Universidad Central de Venezuela, Caracas, Venezuela), and we acknowledge Rogier Donders (Dept of Health Evidence, Radboud University Medical Centre) for statistics support. ER -