TY - T1的白细胞介素- 6的生物标志物thma: hype or is there something else? JF - European Respiratory Journal JO - Eur Respir J SP - 979 LP - 981 DO - 10.1183/13993003.01597-2016 VL - 48 IS - 4 AU - Poynter, Matthew E. AU - Irvin, Charles G. Y1 - 2016/10/01 UR - //www.qdcxjkg.com/content/48/4/979.abstract N2 - Much of precision medicine research today seeks to find a biomarker, or like King Richard, our kingdom might be lost. The hope is that if one is successful in identifying such a biomarker [1], all will be resolved: diagnosis, prognosis and the best treatment regime identified from the morass of treatment options available. In this context, the research for a single, do-all biomarker is a truly dramatic irony because it may not exist, consider the rise and fall of C-reactive protein (CRP) or exhaled nitric oxide fraction (FeNO). Yet such a biomarker could be quite useful in asthma, a syndrome that so often defies definition. With this mythical biomarker, one could clearly decide whether the patient has asthma, assess how severe the disease is, and even guide selection of which of the many available treatment regimens should be employed.Tantalising evidence purports IL-6 to be a biomarker for adult-onset asthma that predicts ICS use and symptoms http://ow.ly/bhra303fg5j ER -