TY -的T1 Transbronchial针愿望peripheral pulmonary lesions: a systematic review and meta-analysis JF - European Respiratory Journal JO - Eur Respir J SP - 196 LP - 204 DO - 10.1183/13993003.00051-2016 VL - 48 IS - 1 AU - Mondoni, Michele AU - Sotgiu, Giovanni AU - Bonifazi, Martina AU - Dore, Simone AU - Parazzini, Elena Maria AU - Carlucci, Paolo AU - Gasparini, Stefano AU - Centanni, Stefano Y1 - 2016/07/01 UR - //www.qdcxjkg.com/content/48/1/196.abstract N2 - Fluoroscopy-guided transbronchial needle aspiration (TBNA) has long been used in the diagnosis of peripheral pulmonary lesions (PPLs), although its diagnostic performance varies considerably.We conducted a systematic review and meta-analysis evaluating the accuracy of TBNA in the diagnosis of PPLs, comparing its diagnostic yield with transbronchial biopsy (TBB) and assessing the main predictors of a successful aspirate.In 18 studies, the overall TBNA yield was 0.53 (95% CI 0.44–0.61). TBNA showed a higher accuracy when directly compared to TBB (0.60 (95% CI 0.49–0.71) versus 0.45 (95% CI 0.37–0.54)). The subgroup analyses documented a higher TBNA yield when the computed tomography (CT) bronchus sign was present (0.70 (95% CI 0.63–0.77) versus 0.51 (95% CI 0.38–0.64)), when rapid on-site evaluation (ROSE) was performed (0.62 (95% CI 0.43–0.79) versus 0.51 (95% CI 0.42–0.60)), in the case of malignant lesions (0.55 (95% CI 0.44–0.66) versus 0.17 (95% CI 0.11–0.24)) and for lesions >3 cm (0.81 (95% CI 0.73–0.87) versus 0.55 (95% CI 0.47–0.63)).Conventional TBNA is a useful sampling technique for the diagnosis of PPL, with a higher diagnostic yield than TBB. The presence of CT bronchus sign, an underlying malignant process, lesion size >3 cm and ROSE employment are predictors of a higher yield.Fluoroscopy-guided transbronchial needle aspiration is a useful technique in diagnosing peripheral pulmonary lesions http://ow.ly/4mK0sB ER -